As healthcare systems move toward greater interoperability, they have leveraged various strategies including cloud-based technology implementation and stakeholder partnerships. Nevertheless, they continue to confront barriers in their efforts. Kristian Feterik, medical director of interoperability and clinical associate professor of medicine at University of Pittsburgh Medical Center (UPMC), explains how widespread adoption of FHIR would advance the healthcare industry's interoperability--and intraoperability--goals as well as how cloud-based technologies factor into this effort.